Combi-Kel

Each 100 ml contains

• Procaine benzyl penicillin : 20 000 000 I.U.( eq. 20 g benzyl penicillin)
• Dihydrostreptomycin sulphate  20 000 000 I.U  (eq. 20 g streptomycin)

Combi-Kel has bactericidal effect through  two mode of actions:

1. Penicillin kills bacteria through binding of the beta-lactam ring to DD-transpeptidase that catalyzes the final step in cell wall biosynthesis, resulting  prevention the new cell wall formation. Penicillin is most effective against gram-positive bacteria that have thick cell walls containing high levels of peptidoglycan.
2. Streptomycin works by Its binds to the small 16 S rRNA of the 30S subunit of the bacterial ribosome, interfering with the binding of formyl-methionyl-tRNA to the 30S subunit. This leads eventual inhibition of protein synthesis and ultimately death of microbial cells.

1. Combi-Kel is two antibiotics in one product.
2. Combi-Kel is a broad spectrum antibiotic affect on gram negative and gram positive bacteria.
3. Combi-Kel has a bactericidal action through destruction of cell wall and inhibition of  protein synthesis of bacteria
4. Combi-Kel rapidly absorbed as it reaches to the maximum blood plasma level within 2 hours after injection.
5. Combi-Kel excreted mainly through bile secretion so didn’t have any side effects on the kidney.
6. Combi-kel characterized by high safety margin 3 times the recommended dosage.

1. Combi-Kel used for effective treatment of Clostridium perfringens (Necrotic enteritis)
2. Used Efficiently to control e.coli and salmonella infection in poultry.
3. Combi-Kel used to control CRD; in combination with ,  Spiramycin, or Cefotaxime and or Lincomycin.
4. Used for treatment of infectious arthritis caused by staphylococcus
5. Combi-Kel used for control of fowl cholera and coryza

For adult Birds:

– 250 ml bottle / for 2500 kg live body weight intramuscular or subcutaneous injection

Meat: 5 days

Egg : 8 weeks